Medication Reviews: A Clinical Approach to Improve Safety, Optimize Therapy, and Reduce Costs

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Sundas Azim, Pharmacy Intern, and Patricia Powers, PharmD, BCPS, Senior Director, Clinical Services

Unmanaged medication use is a hidden cost driver for health plans managing medically complex Medicare Advantage members. What are the hidden costs? Fragmented prescribing, poor adherence, preventable adverse drug events that lead to hospitalizations, lower STAR performance, and rising pharmacy spend.

At RxAnte, our Mosaic Pharmacy Service delivers comprehensive, clinically guided medication reviews as part of a broader pharmacy care management solution. This encounter isn’t just about member engagement—it’s a strategic lever that improves outcomes and supports plan performance.

A medication review is a clinical assessment of all prescriptions, over-the-counter products, supplements, and herbal remedies a member is taking.


Key Benefits of Medication Reviews for Health Plans:

  • Improves Patient Safety

Unnecessary or duplicative prescriptions, unsafe drug combinations, and inappropriate therapies are identified and addressed—reducing the risk of adverse drug events, hospitalizations, and clinical decline.

  • Supports Medication Adherence

    Regimen simplification, patient education, and reminder strategies drive higher adherence among traditionally non-adherent, high-risk members—impacting quality scores and health outcomes.

    • Reduces Total Cost of Care

    By proactively managing complex medication profiles, we help avoid emergency department visits, hospitalizations, and unnecessary pharmacy spend.

    • Boosts Quality Performance

    Medication reviews directly support CMS STAR Ratings and HEDIS metrics by improving adherence, medication reconciliation, and member satisfaction.

    • Enhances Clinical Oversight

    We coordinate across prescribers, pharmacies, and care teams, providing the full-picture medication management that retail pharmacies and time-constrained PCPs often cannot.


    Medication reviews are a critical part of population health strategy. Let us help you reduce risk, improve outcomes, and elevate the standard of care for your members.

    Contact us to explore how Mosaic can support your plan’s performance and member health.

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